Endocrine Abstracts

Objective: Diabetes mellitus is among the most common of chronic disorders with increasing prevalence worldwide, affecting 50 000 citizens in Montenegro. The insulin pump is a medical device that works on the principle of continuous insulin injection, and is used in the control of diabetes in insulin dependent patients. The objective of this study was to highlight the role of nurse in education of the patients, implantation of insulin pump and nursing networking for insulin pu...

Introduction: Juvenile dermatomyositis may be associated with advanced calcinosis but the mechanism that leads to their development remains unclear.Case report: A female patient admitted to the hospital at the age of 17 for skin rash, malaise and pain in peripheral joints and muscles. Congenital bilateral hip dysplasia. After evaluation a syndrome overlap with dominant atypical dermatomyositis and SLE was suspected and treatment with prednisolone and cho...

Diabetic ketoacidosis (DKA) is a state of absolute or relative insulin deficiency characterized by hyperglycemia, metabolic acidosis and ketosis and occurs mainly in type 1 diabetes mellitus (DM). While enhanced lipolysis and inhibition of lipoprotein lipase in DKA lead to typically not severe elevation of triglyceride (TG) level, extreme hypertriglyceridemia (HTG) is rarely seen. If complicated with acute pancreatitis (AP), DKA and HTG form a scarcely reported triad, controve...

Introduction: American Heart Association considers diabetes mellitus (DM) to be one of seven major controllable risk factors for cardiovascular disease. At least 68% of patients age 65 or older with DM die from some form of heart disease while 16% die as a consequence of stroke. Studies conducted in patients with type 2 DM (T2DM) have not confirmed a significant association between a certain types of glucose-lowering drugs and a presence of cardiovascular events.<p class="...

Objective: To evaluate and compare the effects of metformin used as a single-agent therapy and in combination with gliclazide modified release (MR) on glycoregulation and lipid profile in patients with type 2 diabetes mellitus (T2DM).Methodology: A multi-center observational epidemiological study was carried out in patients with T2DM, divided in two groups according to the current type of treatment: first group was on monotherapy with metformin in daily ...

Background: Due to its efficacy and safety, metformin is the most commonly used drug in a single-agent therapy of type 2 diabetes mellitus (T2DM), after lifestyle modifications failed to obtain a desirable effects. Despite his main effects in improving glycemic control, it is also stated that it has a beneficial effects on lipid profile, which may be attributable to improved insulin sensitivity, weight loss and reduction of irreversibly glycated low density lipoprotein cholest...